Extreme obesity and leptin receptor deficiency. A case report
نویسندگان
چکیده
Leptin is vital for maintaining energy homeostasis, by controlling food intake and regulating expenditure (fatty acids). It also participates in glycemic thyroid activity, reproductive immune functions. resistance a phenomenon that appears gradually does not simultaneously affect all organs tissues equally. In models of obesity induced high-fat diet, leptin initially manifests the hypothalamus. This type central can justify an alteration eating patterns (hyperphagia) decrease sympathetic tone, which contribute to increase fat deposits adipose tissue
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ژورنال
عنوان ژورنال: Gaceta médica de Caracas
سال: 2022
ISSN: ['0367-4762']
DOI: https://doi.org/10.47307/gmc.2022.130.3.14